Development of methodologies for risk assessment of contaminated sites, especially mercury pollution in and around Idrija
Research on mercury biogeochemical cycling in terrestrial and aquatic ecosystems
Modelling of mercury cycling in terrestrial and aquatic ecosystems with emphasis on the development of an erosion model in the catchment of the river Idrijca
Research on the metabolism of some metals and metalloids (Hg, Cd, Pb, As, Se) in humans, animals, plants and cell cultures with emphasis on the following studies:
Biotransformations and kinetics of single elements (Hg, As, Se)
Studies of cellular defence and resistance mechanisms against metal toxicity, especially selenium accumulation and excretion and induction of some proteins (metallothioneins, selenoprotein P)
Incorporation of selenium into selenoproteins and metallothioneins
Influence of pollutants on oxidative stress and lysosomal membrane damage
Cooperation in wider medical and public health research, for example:
Influence of arsenic trioxide on different forms of cancer (acute promyelocytic leukaemia, multiple myeloma, astrocytoma)
Mechanisms of mercury retention with selenium in retired miners from the Idrija mercury mine
Professional exposure to mercury
Influence of Tiomersal on dialysis patients and children
Influence of dietary mercury intake on man, in particular newborns
Development of chemical and biological methods for monitoring environmental pollution
Development of analytical techniques for arsenic speciation (AsIII, AsV, monomethyl arsenic and dimethyl arsinic acid, arsenobetaine, trimethylarsenic oxide, trimethylarsonium ion and the four most common arsenosugars) and antimony (SbIII and SbV)
Development of analytical methods for speciation of mercury in biological and environmental samples (total Hg, MeHg, EtHg, DMHg, Hg(II), Hg(0), chemical fractionation of mercury)
Speciation of mercury in air (Hg(0), reactive and particulate Hg)
Methods for following mercury transformations using stable and radioactive isotope tracers
Metrology in environmental measurements (certification of reference materials, organisation of comparison tests and education)
Participation in standardisation of analytical methods
Development of methodologies for data analysis using artificial intelligence and machine learning tools
Technological research areas:
Mass balances of pollutants in industrial processes with emphasis on combustion of fossil fuels (coal, oil and natural gas), waste incinerators and cement factories
Mercury cycling in biological waste treatment plants
Technologies for mercury removal from waste and contaminated areas
Bioremediation of contaminated areas
Tracking tectonic activity (together with the Centre for Radon)